PLEDs on an EEG are indicative of which condition?

PLEDs, or periodic lateralized epileptiform discharges, on an EEG are particularly associated with acute cerebral infarction. These discharges typically reflect localized cortical irritation and are often seen in the context of significant brain pathology, such as stroke. In cases of acute cerebral infarction, the brain tissue that is affected can exhibit these discharges, making the presence of PLEDs an important EEG finding that suggests underlying structural brain damage, often due to ischemia or infarction.

In contrast to the options provided, chronic migraines, tumors in the brain, and seizure disorders do not typically present with PLEDs. Chronic migraines are usually not associated with periodic lateralized discharges, and while seizures may show discharges on an EEG, they do not specifically produce the PLED pattern seen with acute cerebral injuries. Tumors may also cause various EEG abnormalities, but PLEDs are more indicative of the acute processes rather than the chronic conditions associated with tumors.