What EEG pattern is characteristic of Creutzfeldt-Jakob disease?

The EEG pattern that is characteristic of Creutzfeldt-Jakob disease is periodic sharp waves. This pattern typically appears as bursts of rhythmic spikes or sharp waves at regular intervals and is indicative of the underlying neurodegenerative process associated with the disease. This distinctive EEG feature can help differentiate Creutzfeldt-Jakob disease from other forms of dementia and encephalopathy.

Periodic sharp wave complexes are often seen in the latter stages of the disease and can provide important diagnostic clues, particularly when clinical features point toward a prion disease. The presence of these sharp wave patterns correlates with the rapid progression of cognitive decline and neurological symptoms typical of Creutzfeldt-Jakob disease.

Understanding the significance of this EEG finding is crucial for clinicians, as it aids in the diagnosis and management of patients presenting with neurodegenerative disorders.